Protein Details: P2X purinoceptor 6

Protein ID

ICDB_Pro_0587

Protein Name

P2X purinoceptor 6

Gene Name

P2rx6; P2rxl1

Organism

Rattus norvegicus (Rat)

Length

389 amino acids

AlphaFoldDB

AF-P51579-F1-model_v4.pdb

Function

Receptor for ATP that acts as a ligand-gated ion channel.

Sequence

MQLQPAGTGSMASAVAAALVSWGFLDYKTEKYVMTRNCWVGISQRLLQLGVVVYVIGWALLAKKGYQEWDMDPQISVITKLKGVSVTQVKELEKRLWDVADFVRPSQGENVFFLVTNFLVTPAQVQGRCPEHPSVPLANCWADEDCPEGEMGTYSHGIKTGQCVAFNGTHRTCEIWSWCPVESSAVPRKPLLAQAKNFTLFIKNTVTFNKFNFSRTNALDTWDNTYFKYCLYDSLSSPYCPVFRIGDLVAMTGGDFEDLALLGGAVGINIHWDCNLDTKGSDCSPQYSFQLQERGYNFRTANYWWAASGVESRSLLKLYGIRFDILVTGQAGKFALIPTAITVGTGAAWLGMVTFLCDLLLLYVDREAGFYWRTKYEEARAPKATTNSA

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1006/bbrc.1996.0915; 10.1038/nature02426; 10.1523/jneurosci.16-08-02495.1996

RefSeq

NP_036853.2